About Mr. David Manne

David Raju Manne is a senior Healthcare & Life Sciences executive, advisor, and international speaker with over 23 years of experience leading healthcare transformation at the intersection of patient safety, clinical operations, and digital innovation. His career spans healthcare consulting, hospital operations, EHR modernization, and AI-driven transformation, with leadership roles across North America, Europe, and APAC.

David brings a unique blend of clinical workflow understanding, regulatory rigor, and applied AI leadership. He has held senior positions with EXL, Atos (Anthelio Healthcare), Microsoft, Tech Mahindra, and Apollo Hospitals Group, where he led multi-million-dollar programs focused on reducing clinical risk, improving care quality, and strengthening safety governance through technology.

A core focus of David’s work is the practical application of AI to patient safety. He has designed and delivered AI-enabled solutions that:

• Detect clinical risk early by analyzing unstructured and structured EHR data (labs, notes, vitals) to flag patient deterioration and safety events.


• Reduce medication and pharmacy-related errors using AI-driven prior authorization intelligence, formulary validation, and controlled-substance monitoring.


• Improve diagnostic accuracy and care continuity through intelligent ingestion and normalization of lab and imaging data into EHR workflows.


• Prevent adverse events by embedding AI-powered alerts and predictive analytics directly into clinician workflows—minimizing alert fatigue while improving signal quality.


• Strengthen regulatory and quality compliance, using AI to monitor documentation completeness, protocol adherence, and audit readiness (ONC, GDPR, HIPAA).

David has also led AI safety-by-design initiatives, ensuring that automation, GenAI, and decision-support systems are clinically explainable, auditable, and aligned with patient safety standards rather than introducing new risk.

He is the author and presenter of “AI-Driven Innovation: Transforming Healthcare Leadership and Patient Outcomes” at ICIMTH 2025 (Athens, Greece), and has published earlier work on healthcare IT and patient safety, including “Healthcare Information Technology – An Enabler or a Hazard for Patient Safety”. His thought leadership bridges clinical safety principles with modern AI capabilities, addressing both opportunity and risk.

As a speaker, David is known for translating complex AI concepts into practical patient safety strategies for healthcare leaders—covering topics such as AI governance, human-in-the-loop design, bias mitigation, and safe deployment at scale. His sessions are highly relevant to CIOs, CMIOs, quality leaders, clinicians, and policymakers navigating AI adoption in regulated healthcare environments.

Currently, David serves as Senior Assistant Vice President – Consulting & Operations (Healthcare & Life Sciences) at EXL, where he advises healthcare organizations on AI adoption with a strong emphasis on patient safety, clinical quality, and operational resilience.

Core Speaking Themes

• AI for Patient Safety: From Risk Detection to Prevention


• Clinical Decision Support Without Alert Fatigue


• Safe Use of Generative AI in Healthcare


• AI Governance, Explainability & Regulatory Readiness


• EHR Modernization as a Foundation for Patient Safety


• Leadership Lessons in Scaling AI Safely in Healthcare